Susanne Franssen

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research interests:

• Molecular evolution and adaptation to new environments
• Identification of signatures of selection
• Haplotype analysis
• Population genetics
• Transcriptome & expression analysis, allele specific expression
• Application of Next generation sequencing technologies

During my doctoral studies I investigated expression divergence of natural seagrass populations from different temperature regimes in response to realistic heat stress scenarios. These analyses gained insights into population differences that suggest adaptive benefit as well as addressed fundamental issues in expression analysis in non-genetic model organisms.

In my current work I focus on the more detailed mechanisms that can lead to population divergence. This is done via an experimental evolution approach in Drosophila populations that are exposed to a novel laboratory environment over multiple generations. In the experimental setup, next generation whole genome sequencing is employed to assess population changes over time with the focus to identify selected sites / signatures of selection. I am particularly interested in the effect of linkage between SNPs and the change of haplotype structure during the course of experimental evolution.

Publications