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Thomas Flatt

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Flatt, T. 2009. Ageing: Diet and Longevity in the Balance, Nature 462:989-990. Pdf

Flatt, T., and P.S. Schmidt. 2009. Integrating evolutionary and molecular genetics of aging. In: Masoro, E. J. (editor), “Biochemical and Molecular Mechanisms of Aging - from Model Systems to Human Longevity”, Biochimica et Biophysica Acta (BBA – General Subjects) 1790:951-962. Pdf

Bauer, J.H., Morris, S.N.S., Chang, C., Flatt, T., Wood, J.G., and S.L. Helfand. 2009. dSir2 and Dmp53 interact to mediate aspects of CR-dependent life span extension in D. melanogaster. Impact AGING 1(1):38-48. [Featured in Donehower, L.A., 2009, Longevity regulation in flies: a role for p53, in Impact AGING]. Pdf

Flatt, T., Heyland, A., Rus, F., Porpiglia, E., Sherlock, C., Yamamoto, R., Garbuzov, A., Palli, S.R., Tatar, M., and N. Silverman. 2008. Hormonal regulation of the humoral innate immune response in Drosophila melanogaster. Journal of Experimental Biology 211: 2712-2724. [Image Featured in JEB 2009 Calendar]. Pdf

Flatt, T., Min, K.-J., D’Alterio, C., Villa-Cuesta, E., Cumbers, J., Lehmann, R., Jones, D.L., and M. Tatar. 2008. Drosophila germ-line modulation of insulin signaling and lifespan. Proceedings of the National Academy of Sciences USA 105:6368-6373. [Featured in Partridge, L., 2008, Some highlights of research on aging with invertebrates, 2008, in Aging Cell, and in many specific and general interest news outlets]. Pdf

Crook, T.C., Flatt, T., and P.T. Smiseth. 2008. Hormonal modulation of larval begging and growth in the burying beetle Nicrophorus vespilloides. Animal Behaviour 75:71-77. Pdf

Flatt, T., and D.E.L. Promislow. 2007. Physiology: still pondering an age-old question. Science 318:1255-1256. [Invited Perspective]. Pdf

Flatt, T., and T.J. Kawecki. 2007. Juvenile hormone as a regulator of the trade-off between reproduction and life span in Drosophila melanogaster. Evolution 61:1980-1991. Pdf

Shingleton, A., Frankino, W.A., Flatt, T., Nijhout, H.F., and D. Emlen. 2007. Size and shape: the developmental regulation of static allometry in insects. BioEssays 29:536-548. [Invited Review]. Pdf

Min, K.-J., Flatt, T., Kulaots, I., and M. Tatar. 2007. Counting calories in Drosophila dietary restriction. Experimental Gerontology 42:247-251. Pdf

Flatt, T., Moroz, L. L., Tatar, M., and A. Heyland. 2006. Comparing thyroid and insect hormone signaling. Integrative & Comparative Biology 46:777-794. Pdf

Bishop, C., Erezyilmaz, D.F., Flatt, T., Georgiou, C.D., Hadfield, M., Heyland, A., Hodin, J., Jacobs, M., Maslakova, S.A., Pires, A., Reitzel, A., Santagata, S., Tanaka, K., and J.H. Youson, 2006. What is metamorphosis? Integrative & Comparative Biology 46:655-661. Pdf

Braendle, C., and T. Flatt. 2006. A role for genetic accommodation in evolution? BioEssays 28:868-873. [Invited Commentary]. Pdf

Killingback, T., Bieri, J., and T. Flatt. 2006. Evolution in group-structured populations can resolve the tragedy of the commons. Proceedings of the Royal Society of London B 273:1477-1481. Pdf

Tu, M.P., Flatt, T., and M. Tatar. 2006. Juvenile and steroid hormones in Drosophila melanogaster longevity. Chapter 16 (pp. 415-448) in Handbook of the Biology of Aging, 6th Edition (Editors: Edward J. Masoro and Steven N. Austad), Academic Press (Elsevier), San Diego. [Invited Book Chapter]. Pdf

Flatt, T., Tu, M.-P., and M. Tatar. 2005. Hormonal pleiotropy and the juvenile hormone regulation of Drosophila development and life history. BioEssays 27:999-1010. [Invited Review, With Cover Image]. Pdf

Flatt, T. 2005. The evolutionary genetics of canalization. Quarterly Review of Biology 80:287-316. Pdf

Altwegg, R., Dummermuth, S., Anholt, B.R., and T. Flatt. 2005. Winter weather affects asp viper (Vipera aspis aspis) population dynamics through susceptible juveniles. Oikos 110:55-66. Pdf

Flatt, T., and T.J. Kawecki. 2004. Pleiotropic effects of Methoprene-tolerant (Met), a gene involved in juvenile hormone metabolism, on life history traits in Drosophila melanogaster. Genetica 122:141-160. Pdf

Flatt, T., and I. Scheuring. 2004. Stabilizing factors interact in promoting host-parasite coexistence. Journal of Theoretical Biology 228:241-249. Pdf

Flatt, T. 2004. Assessing natural variation in genes affecting Drosophila lifespan. Mechanisms of Ageing and Development 125:155-159. [Invited Editorial]. Pdf

Rauch, G., Simon, J.-C., Chaubet, B., Haack, L., Flatt, T., and W.W. Weisser. 2002. The influence of ant attendance on aphid feeding behaviour investigated with the electrical penetration graph technique. Entomologia Experimentalis et Applicata 102:13-20. Pdf

Flatt, T., Shine, R., Borges-Landaez, P.A., and S.J. Downes. 2001. Phenotypic variation in an oviparous montane lizard: effects of thermal and hydric incubation environments. Biological Journal of the Linnean Society 74:339-350. Pdf

Flatt, T., Maire, N., and M. Doebeli. 2001. A bit of sex stabilizes host-parasite dynamics. Journal of Theoretical Biology 212:345-354. Pdf

Flatt, T., and W.W. Weisser. 2000. The effects of mutualistic ants on aphid life-history traits. Ecology 81:3522-3529. Pdf

Flatt, T., Dummermuth, S., and B.R. Anholt. 1997. Mark-recapture estimates of survival in populations of the asp viper, Vipera aspis aspis. Journal of Herpetology 31:558-564. Pdf

Published Abstracts

Flatt, T. 2006. Life history pleiotropy mediated by Methoprene-tolerant, a putative juvenile hormone receptor. Journal of Experimental Zoology A – Comparative Experimental Biology 305A:126.

Flatt, T. 2005. Juvenile hormone as an effector of metamorphosis and life history transitions. Integrative & Comparative Biology 45:997.

Edited Book

Flatt, T., and A. Heyland (Editors). Mechanisms of Life History Evolution. Oxford University Press, Oxford, UK. In Preparation for 2011.

 

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